Shared Facilities

Current Projects

3 Research Projects:
Project Topic Funding Agency Details
Animal Model Systems Animal Imaging, Contrast Agent Chemistry, Physiology and ADME-Tox, Targeting Ligand Development, Tumor Biology and Cytotherapy  TSA, NCI Details
Cytotoxic and Radio Therapy Tumor Biology and Cytotherapy  TSA, Lewis, Ellison Details
High-Throughput Drug Discovery Targeting Ligand Development  TSA, NCI, Ellison, Gorin Details
Description:The discovery of new diagnostic and therapeutic agents for human disease requires well designed animal model systems. The Center for Molecular Imaging employs state-of-the-art molecular and cellular biology to produce novel animal models for a wide variety of human diseases. These models are used to optimize the next generation of disease-specific contrast agents.
Description:At the Center for Molecular Imaging, we believe that Seeing is Curing™. If we are able to see cancer and other diseases using targeted small molecule, and learn how to better target disease using the techniques of molecular imaging, then we should be able to kill cancer by replacing the “light bulb” with a “bomb.” Many sub-projects are focused on developing the next generation of disease-targeted molecular therapies, which have improved therapeutic window by virtue of lowered background, non-specific binding.
Description:At the present time, the world has few effective small molecules that bind with high affinity and specificity to cancer and other human diseases. The Center for Molecular Imaging has invested heavily in the development of robotic chemistry techniques to speed the rate at which new targeting ligands are discovered and new therapeutic combinations are discovered.